On-Chip DNA Methylation Analysis Using Osmium Complexation
نویسندگان
چکیده
منابع مشابه
On-Chip DNA Methylation Analysis Using Osmium Complexation
The development of a reaction for detecting the presence/absence of one methyl group in a long DNA strand is a chemically and biologically challenging research subject. A newly designed chemical assay on a chip for the typing of DNA methylation has been developed. A methylation-detection probe fixed at the bottom of microwells was crosslinked with methylated DNA mediated by osmium complexation ...
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ژورنال
عنوان ژورنال: Journal of Nucleic Acids
سال: 2011
ISSN: 2090-021X
DOI: 10.4061/2011/480570